--- a/browser/components/enterprisepolicies/Policies.jsm
+++ b/browser/components/enterprisepolicies/Policies.jsm
@@ -409,17 +409,22 @@ var Policies = {
           }
         });
       }
       if ("Uninstall" in param) {
         runOncePerModification("extensionsUninstall", JSON.stringify(param.Uninstall), () => {
           AddonManager.getAddonsByIDs(param.Uninstall, (addons) => {
             for (let addon of addons) {
               if (addon) {
-                addon.uninstall();
+                try {
+                  addon.uninstall();
+                } catch (e) {
+                  // This can fail for add-ons that can't be uninstalled.
+                  // Just ignore.
+                }
               }
             }
           });
         });
       }
       if ("Locked" in param) {
         for (let ID of param.Locked) {
           manager.disallowFeature(`modify-extension:${ID}`);