--- a/browser/app/profile/firefox.js
+++ b/browser/app/profile/firefox.js
@@ -1259,17 +1259,17 @@ pref("browser.newtabpage.rows", 3);
 
 // number of columns of newtab grid
 pref("browser.newtabpage.columns", 5);
 
 // directory tiles download URL
 pref("browser.newtabpage.directory.source", "https://tiles.services.mozilla.com/v3/links/fetch/%LOCALE%/%CHANNEL%");
 
 // activates Activity Stream
-pref("browser.newtabpage.activity-stream.enabled", true);
+pref("browser.newtabpage.activity-stream.enabled", false);
 pref("browser.newtabpage.activity-stream.prerender", true);
 pref("browser.newtabpage.activity-stream.aboutHome.enabled", true);
 
 pref("browser.library.activity-stream.enabled", true);
 
 // Enable the DOM fullscreen API.
 pref("full-screen-api.enabled", true);
 

--- a/browser/base/content/test/about/browser.ini
+++ b/browser/base/content/test/about/browser.ini
@@ -9,16 +9,17 @@ support-files =
   searchSuggestionEngine.xml
   test_bug959531.html
   POSTSearchEngine.xml
 
 [browser_aboutCertError.js]
 [browser_aboutHealthReport.js]
 skip-if = os == "linux" # Bug 924307
 [browser_aboutHome_imitate.js]
+skip-if = os == "win" && debug && !e10s # Bug 1411797
 [browser_aboutHome_input.js]
 skip-if = os == "win" && debug && !e10s # Bug 1399648
 [browser_aboutHome_search_POST.js]
 [browser_aboutHome_search_composing.js]
 skip-if = !debug && (os == "mac" || (os == "linux" && bits == 32)) # Bug 1400491, bug 1399648
 [browser_aboutHome_search_searchbar.js]
 [browser_aboutHome_search_suggestion.js]
 skip-if = os == "mac" || (os == "linux" && !debug) # Bug 1399648

--- a/browser/components/newtab/tests/xpcshell/test_AboutNewTabService.js
+++ b/browser/components/newtab/tests/xpcshell/test_AboutNewTabService.js
@@ -25,17 +25,17 @@ function cleanup() {
   aboutNewTabService.resetNewTabURL();
 }
 
 do_register_cleanup(cleanup);
 
 add_task(async function test_as_and_prerender_initialized() {
   Assert.equal(aboutNewTabService.activityStreamEnabled, Services.prefs.getBoolPref(ACTIVITY_STREAM_PREF),
     ".activityStreamEnabled should be set to the correct initial value");
-  Assert.equal(aboutNewTabService.activityStreamPrerender, Services.prefs.getBoolPref(ACTIVITY_STREAM_PRERENDER_PREF),
+  Assert.equal(aboutNewTabService.activityStreamPrerender, Services.prefs.getBoolPref(ACTIVITY_STREAM_PREF),
     ".activityStreamPrerender should be set to the correct initial value");
   Services.prefs.getBoolPref(ACTIVITY_STREAM_PREF);
 });
 
 /**
  * Test the overriding of the default URL
  */
 add_task(async function test_override_activity_stream_disabled() {

--- a/browser/components/search/test/browser_searchEngine_behaviors.js
+++ b/browser/components/search/test/browser_searchEngine_behaviors.js
@@ -100,18 +100,18 @@ function promiseStateChangeURI() {
     }
 
     gBrowser.addProgressListener(listener);
   });
 }
 
 function promiseContentSearchReady(browser) {
   return ContentTask.spawn(browser, {}, async function(args) {
-    await ContentTaskUtils.waitForCondition(() => content.wrappedJSObject.gContentSearchController &&
-      content.wrappedJSObject.gContentSearchController.defaultEngine
+    await ContentTaskUtils.waitForCondition(() => (content.wrappedJSObject.gContentSearchController ||
+      (content.wrappedJSObject.gSearch || {})._contentSearchController || {}).defaultEngine
     );
   });
 }
 
 add_task(async function() {
   await SpecialPowers.pushPrefEnv({ set: [
     ["browser.search.widget.inNavBar", true],
   ]});

--- a/browser/extensions/screenshots/test/browser/browser.ini
+++ b/browser/extensions/screenshots/test/browser/browser.ini
@@ -1,5 +1,6 @@
 [DEFAULT]
 support-files =
   head.js
 
 [browser_screenshots_ui_check.js]
+skip-if = os == "win" && bits == 64 && debug # Bug 1411797

--- a/browser/modules/test/browser/browser_UsageTelemetry_content_aboutHome.js
+++ b/browser/modules/test/browser/browser_UsageTelemetry_content_aboutHome.js
@@ -35,16 +35,17 @@ add_task(async function setup() {
 
   // Make sure to restore the engine once we're done.
   registerCleanupFunction(async function() {
     Services.search.currentEngine = originalEngine;
     Services.search.removeEngine(engineDefault);
     Services.search.removeEngine(engineOneOff);
     await PlacesTestUtils.clearHistory();
     Services.telemetry.setEventRecordingEnabled("navigation", false);
+    Services.prefs.clearUserPref("browser.newtabpage.activity-stream.enabled");
     Services.prefs.clearUserPref("browser.newtabpage.activity-stream.aboutHome.enabled");
   });
 });
 
 add_task(async function test_abouthome_simpleQuery() {
   // Make sure Activity Stream about:home is disabled.
   Services.prefs.setBoolPref("browser.newtabpage.activity-stream.aboutHome.enabled", false);
 
@@ -93,16 +94,17 @@ add_task(async function test_abouthome_s
   events = (events.parent || []).filter(e => e[1] == "navigation" && e[2] == "search");
   checkEvents(events, [["navigation", "search", "about_home", "enter", {engine: "other-MozSearch"}]]);
 
   await BrowserTestUtils.removeTab(tab);
 });
 
 add_task(async function test_abouthome_activitystream_simpleQuery() {
   // Make sure Activity Stream about:home is enabled.
+  Services.prefs.setBoolPref("browser.newtabpage.activity-stream.enabled", true);
   Services.prefs.setBoolPref("browser.newtabpage.activity-stream.aboutHome.enabled", true);
 
   // Let's reset the counts.
   Services.telemetry.clearScalars();
   Services.telemetry.clearEvents();
   let search_hist = getAndClearKeyedHistogram("SEARCH_COUNTS");
 
   let tab = await BrowserTestUtils.openNewForegroundTab(gBrowser);

--- a/dom/indexedDB/test/browser.ini
+++ b/dom/indexedDB/test/browser.ini
@@ -12,10 +12,11 @@ support-files =
   browser_permissionsWorker.js
   bug839193.js
   bug839193.xul
 
 [browser_forgetThisSite.js]
 [browser_permissionsPromptAllow.js]
 [browser_permissionsPromptDeny.js]
 [browser_permissionsPromptWorker.js]
+skip-if = os == "win" && debug && e10s # Bug 1411797
 [browser_perwindow_privateBrowsing.js]
 [browser_bug839193.js]